Fundamentals Of Organic Chemistry (7th Edition)

Fundamentals of Organic Chemistry (7th Edition)

Name: Fundamentals of Organic Chemistry
Edition: 7th
Author: John McMurry
Subject: Organic Chemistry
Language: English
Publisher: Brooks/Cole, Cengage Learning

Brief Introduction

Organic chemistry is changing rapidly. From its early days dealing primarily with soaps and dyes, organic chemistry has moved to center stage in many fields, from molecular biology to medicine and from agriculture to advanced electronics.Today’s organic chemists are learning new languages—particularly those of medicine and molecular biology—to shape the world we live in, and practitioners in many other fi elds are fi nding themselves having to learn something of organic chemistry.

More than ever before, a fundamental understanding of organic chemistry is critical to addressing complex, interdisciplinary problems. This seventh edition of Fundamentals of Organic Chemistry addresses some of the changes that are occurring by placing a greater emphasis on the applications of organic chemistry, especially applications to medicine and agriculture. Many new examples of biological organic reactions have been added in this edition; Interlude boxes at the end of each chapter are rich in the chemistry of drugs and agrochemicals; and problem categories such as “In the Field” and “In the Medicine Cabinet” reinforce the emphasis on applications.

Structure and Bonding; Acids and Bases
Alkanes: The Nature of Organic Compounds
Alkenes and Alkynes: The Nature of Organic Reactions
Reactions of Alkenes and Alkynes
Aromatic Compounds
Stereochemistry at Tetrahedral Centers
Organohalides: Nucleophilic Substitutions and Eliminations
Alcohols, Phenols, Ethers, and Their Sulfur Analogs
Aldehydes and Ketones: Nucleophilic Addition Reactions
Carboxylic Acids and Derivatives: Nucleophilic Acyl Substitution Reactions
Carbonyl Alpha-Substitution Reactions and Condensation Reactions
Amines
Structure Determination
Biomolecules: Carbohydrates
Biomolecules: Amino Acids, Peptides, and Proteins
Biomolecules: Lipids and Nucleic Acids
The Organic Chemistry of Metabolic Pathways

APPENDIX A: Nomenclature of Polyfunctional Organic Compounds
APPENDIX B: Glossary
APPENDIX C: Answers to Selected In-Chapter Problems

Excerpts

…
In this and the next three chapters, we’ll focus on the most commonly occurring of all functional groups—those that contain oxygen—beginning in this chapter with a look at compounds that contain C –O single bonds. An alcohol is a compound that has a hydroxyl group bonded to a saturated, sp3-hybridized carbon atom, ROOH; a phenol has a hydroxyl group bonded to an aromatic ring, ArOOH; and an ether has an oxygen atom bonded to two organic groups, ROOOR′. The corresponding sulfur analogs are called thiols (ROSH), thiophenols (ArOSH), and sulfi des (ROSOR′). Alcohols, phenols, and ethers occur widely in nature and have many industrial, pharmaceutical, and biological applications. Ethanol, for instance, is a fuel additive, an industrial solvent, and a beverage; phenol is a general disinfectant, commonly called carbolic acid; and diethyl ether—the familiar “ether” of medical use—is frequently used as a reaction solvent and was once popular as an inhaled anesthetic.
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