Robbins Basic Pathology (10th edition)

Name: Robbins Basic Pathology

Edition: 10th

Author: Vinay Kumar, Stanley L Robbins, Ramzi S. Cotran

Subject: Human Pathology

Language: English

Publisher: Elsevier

Robbins Basic Pathology (10th edition)

Brief Introduction

Robbins Basic Pathology is a lighter, manageable version of Robbins and Cotran Pathologic Basis of Disease, by the same editor team (commonly known among med students as “Big Robbins”).  By highlighting key pathological processes, such as pathogenesis and morphology, this text focuses more on the pertinent information you need to truly understand human pathology without overwhelming you with unnecessary details. As a first year student, you will learn more about the clinical features of a disease, how to apply that knowledge in a hospital setting and of course, how to prepare for those board exams.

The tenth edition is an important milestone in the life of a textbook. This occasion is a propitious time to look back on the origins of Basic Pathology, which are summed up best by quoting Stanley Robbins from the preface of the first edition (1971):

“Of books as well as men, it may be observed that fat ones contain thin ones struggling to get out. In a sense, this book bears such a relationship to its more substantial progenitor, Robbins Pathology. It arose from an appreciation of the modern medical student’s dilemma. As the curriculum has become restructured to place greater emphasis on clinical experience, time for reading is correspondingly curtailed.…In writing this book, rare and esoteric lesions are omitted without apology, and infrequent or trivial ones described only briefly. We felt it important, however, to consider rather fully the major disease entities.”


  1. The Cell as a Unit of Health and Disease
  2. Cell Injury, Cell Death, and Adaptations
  3. Inflammation and Repair
  4. Hemodynamic Disorders, Thromboembolism, and Shock
  5. Diseases of the Immune System
  6. Neoplasia
  7. Genetic and Pediatric Diseases
  8. Environmental and Nutritional Diseases
  9. General Pathology of Infectious Diseases
  10. Blood Vessels
  11. Heart
  12. Hematopoietic and Lymphoid Systems
  13. Lung
  14. Kidney and Its Collecting System
  15. Oral Cavities and Gastrointestinal Tract
  16. Liver and Gallbladder
  17. Pancreas
  18. Male Genital System and Lower Urinary Tract
  19. Female Genital System and Breast
  20. Endocrine System
  21. Bones, Joints, and Soft Tissue Tumors
  22. Peripheral Nerves and Muscles
  23. Central Nervous System
  24. Skin


Pathology literally translates to the study of suffering (Greek pathos = suffering, logos = study); as applied to modern medicine, it is the study of disease. Virchow was certainly correct in asserting that disease originates at the cellular level, but we now realize that cellular disturbances arise from alterations in molecules (genes, proteins, and others) that influence the survival and behavior of cells. Thus, the foundation of modern pathology is understanding the cellular and molecular abnormalities that give rise to diseases. It is helpful to consider these abnormalities in the context of normal cellular structure and function, which is the theme of this introductory chapter. It is unrealistic (and even undesirable) to condense the vast and fascinating field of cell biology into a single chapter. Consequently, rather than attempting a comprehensive review, the goal here is to survey basic principles and highlight recent advances that are relevant to the mechanisms of disease that are emphasized throughout the rest of the book.


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